ISSN 1305-3825 | E-ISSN 1305-3612
General Radiology - Review
The role of dynamic contrast-enhanced MRI in cancer diagnosis and treatment
1 Molecular Imaging Program, National Cancer Institute National Institutes of Health, Bethesda, Maryland, USA  
2 Clinical Center Radiology and Imaging Sciences, National Institutes of Health, Bethesda, Maryland, USA  
3 Philips Healthcare Cleveland, Ohio, USA  
Diagn Interv Radiol ; : 186-192
DOI: 10.4261/1305-3825.DIR.2537-08.1
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Key Words: • pathologic angiogenesis • angiogenic inhibitors • magnetic resonance imaging
Abstract

Angiogenesis is a key step in the pathophysiology of tumor growth and metastatic spread. Recently, dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) has emerged as a method for assessing angiogenesis both during the initial diagnosis and for follow up of anti-angiogenic therapies. In this review, we discuss the technical aspects of implementing DCE-MRI in clinical practice with emphasis on acquisition methods and analytic techniques.

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