Interventional Radiology - Original Article
Diagnostic accuracy and safety of CT-guided fine needle aspiration biopsy of pulmonary lesions with non-coaxial technique: a single center experience with 442 biopsies
Department of Radiology, Ankara University School of Medicine, Ankara Turkey
Department of Biostatistics, Ankara University School of Medicine, Ankara Turkey
Department of Cytopathology, Ankara University School of Medicine, Ankara Turkey
Diagn Interv Radiol ; : -
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Purpose: The purpose of this study was to evaluate the diagnostic accuracy and safety of CT-guided biopsy of pulmonary lesions with fine needle aspiration (FNA) using non-coaxial technique.
Materials and Methods: We analyzed 442 patients who underwent CT-guided lung biopsy with FNA and non-coaxial technique to determine the diagnostic outcomes, complication rates and independent risk factors for diagnostic failure and pneumothorax.
Results: Diagnostic accuracy, sensitivity and specificity were 97.6%, 97.3% and 100%, respectively. The significant risk factors for the diagnostic failure were age and >35 mm lesion size. The rates of pneumothorax and chest tube placement were 19% and 2.9%, respectively. The significant risk factors for the pneumothorax were middle and lower lobe location, lesion to pleura distance >7.5 mm, and >45∘ needle trajectory angle.
Conclusion: CT-guided FNA of pulmonary lesions with non-coaxial technique is a safe and reliable method with a relatively low pneumothorax rate and an acceptably high diagnostic accuracy.