Interventional Radiology - Original Article

Diagnostic accuracy and safety of CT-guided fine needle aspiration biopsy of pulmonary lesions with non-coaxial technique: a single center experience with 442 biopsies

10.5152/dir.2016.16173

  • Çağlar Uzun
  • Zehra Akkaya
  • Ebru Düşünceli Atman
  • Evren Üstüner
  • Elif Peker
  • Başak Gülpınar
  • Atilla Halil Elhan
  • Koray Ceyhan
  • Kayhan Çetin Atasoy

Received Date: 02.04.2016 Accepted Date: 10.07.2016 Diagn Interv Radiol 2017;23(2):137-143

PURPOSE:

We aimed to evaluate the diagnostic accuracy and safety of computed tomography (CT)-guided biopsy of pulmonary lesions with fine needle aspiration (FNA) using non-coaxial technique.

METHODS:

We analyzed 442 patients who underwent CT-guided lung biopsy with FNA and non-coaxial technique to determine the diagnostic outcomes, complication rates, and independent risk factors for diagnostic failure and pneumothorax.

RESULTS:

Diagnostic accuracy, sensitivity, and specificity were 97.6%, 97.3%, and 100%, respectively. Age and >35 mm lesion size were significant risk factors for diagnostic failure. The rates of pneumothorax and chest tube placement were 19% and 2.9%, respectively. Middle and lower lobe location, lesion to pleura distance >7.5 mm, and >45° needle trajectory angle were significant risk factors for pneumothorax.

CONCLUSION:

CT-guided FNA of pulmonary lesions with non-coaxial technique is a safe and reliable method with a relatively low pneumothorax rate and an acceptably high diagnostic accuracy.