ABSTRACT

This report attempts to document the potential of magnetic resonance (MR) tractography in providing detailed information on white matter tract anomalies in schizencephaly. Diffusion tensor imaging with tractography was performed in four patients referred for neuroimaging. On conventional MR imaging, two of the patients had temporal lobe involvement and the other two had frontal lobe involvement. Tractography was successful in showing major tract abnormalities in two patients and subcortical involvement in three. Tractography was negative in one patient. MR tractography is a promising imaging method in developmental anomalies, beneficial for both clinical management and understanding the nature of the pathology.

Keywords: malformations of cortical development, schizencephaly, magnetic resonance imaging