Short-term imaging follow-up of patients with concordant benign breast core needle biopsies: is it really worth it?
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Breast Imaging - Original Article
VOLUME: 20 ISSUE: 6
P: 464 - 469
November 2014

Short-term imaging follow-up of patients with concordant benign breast core needle biopsies: is it really worth it?

Diagn Interv Radiol 2014;20(6):464-469
1. Advanced Imaging of Port Charlotte, Port Charlotte, Florida, USA
2. Department of Radiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA
3. Department of Center for Women’s Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA
No information available.
No information available
Received Date: 27.02.2014
Accepted Date: 08.05.2014
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ABSTRACT

PURPOSE

Women with histologically proven concordant benign breast disease are often followed closely after biopsy for a period of two years, and they are considered to be at high-risk for cancer development. Our goal was to evaluate the utility of short-term (six-month) imaging follow-up and determine the incidence of breast cancer development in this population.

METHODS

Retrospective review of concordant benign breast pathology was performed in 558 patients who underwent multimodality breast core biopsy. A total of 339 patients (60.7%) with 393 biopsies qualified for the study. The six-, 12-, and 24-month incidence rates of breast cancer development were estimated with 95% confidence intervals (CI), using the exact method binomial proportions.

RESULTS

No cancer was detected in 285 of 339 patients (84.1%) returning for the six-month follow-up. No cancer was detected in 271 of 339 patients (79.9%) returning for the 12-month follow-up. Among 207 follow-up exams (61.1%) performed at 24 months, three patients were detected to have cancer in the ipsilateral breast (1.45% [95% CI, 0.30%–4.18%]) and two patients were detected to have cancer in the contralateral breast (0.97% [95% CI, 0.12%–3.45%]). Subsequent patient biopsy rate was 30 of 339 (8.85%, [95% CI, 6.05%–12.39%]). Three ipsilateral biopsies occurred as a sole result of the six-month follow-up of 285 patients (1.05%, [95% CI, 0.22%–3.05%]).

CONCLUSION

Short-term imaging follow-up did not contribute to improved breast cancer detection, as all subsequent cancers were detected on annual mammography. Annual diagnostic mammography after benign breast biopsy may be sufficient.

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