E-ISSN: 1305-3612
Thrombolysis during the endovascular treatment of iliac artery occlusions
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Interventional Radiology - Original Article
VOLUME: 16 ISSUE: 1
P: 84-89
March 2010

Thrombolysis during the endovascular treatment of iliac artery occlusions

Diagn Interv Radiol 2010;16(1):84-89
DOI: 10.4261/1305-3825.DIR.2191-08.3
Giuseppe Taddei 1
Paolo Tamellini 2
Faccioli Niccolo 3
Iannello Antonio 4
1. Departments of Radiology Sacro Cuore Hospital, Negrar, Italy
2. Departments of Surgery Sacro Cuore Hospital, Negrar, Italy
3. Department of Radiology G. B. Rossi University Hospital, Verona, Italy
4. Departments of Surgery Sacro Cuore Hospital, Negrar, Italy
No information available.
No information available
Received Date: 12.08.2008
Accepted Date: 27.07.2009
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ABSTRACT

CONCLUSION

Thrombolysis may give an advantage in approaching the percutaneous treatment of atherosclerotic iliac arterial occlusions.

RESULTS

In 21 of 25 cases (84%), we managed to correctly pass through the iliac occlusion using a guidewire and completed the thrombolysis. In all these cases, thrombolysis caused the complete dissolution of thrombi. All 21 cases with complete thrombolytic treatment had complete recanalization of the iliac axis. Twenty of these 21 cases (95%) were than successfully treated with percutaneous methodologies.

MATERIALS AND METHODS

We retrospectively studied 28 cases of iliac occlusions in 26 patients, occurring over a six-year period. All patients suffered from claudication. Percutaneous treatments were performed using thrombolysis in 25 cases. The average duration of the infusion with urokinase-type plasminogen activator was 28.2 hours (range, 9–48 hours); total dose was 1,820,000 units per hour. The average duration of the follow-up was 46.6 months (range, 2–81 months).

PURPOSE

The purpose of this study was to assess the possible therapeutic advantage of thrombolysis prior to recanalization of iliac occlusions with percutaneous treatment angioplasty and stenting.