E-ISSN: 1305-3612
Use of shear wave elastography to differentiate benign and malignant breast lesions
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Breast Imaging - Original Article
VOLUME: 20 ISSUE: 3
P: 239-244
May 2014

Use of shear wave elastography to differentiate benign and malignant breast lesions

Diagn Interv Radiol 2014;20(3):239-244
DOI: 10.5152/dir.2014.13306
Deniz Çebi Olgun
Bora Korkmazer
Fahrettin Kılıç
Atilla Süleyman Dikici
Mehmet Velidedeoğlu
Fatih Aydoğan
Fatih Kantarcı
Mehmet Halit Yılmaz
1. Department of Radiology, İstanbul University Cerrahpaşa School of Medicine, İstanbul, Turkey
2. Department of General Surgery, İstanbul University Cerrahpaşa School of Medicine, İstanbul, Turkey
3. Departments of General Surgery, İstanbul University, Cerrahpaşa School of Medicine, İstanbul, Turkey
4. From the Departments of Radiology, İstanbul University, Cerrahpaşa School of Medicine, İstanbul, Turkey
No information available.
No information available
Received Date: 15.07.2013
Accepted Date: 27.10.2013
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ABSTRACT

PURPOSE

We aimed to determine the correlations between the elasticity values of solid breast masses and histopathological findings to define cutoff elasticity values differentiating malignant from benign lesions.

MATERIALS and METHODS

A total of 115 solid breast lesions of 109 consecutive patients were evaluated prospectively using shear wave elastography (SWE). Two orthogonal elastographic images of each lesion were obtained. Minimum, mean, and maximum elasticity values were calculated in regions of interest placed over the stiffest areas on the two images; we also calculated mass/fat elasticity ratios. Correlation of elastographic measurements with histopathological results were studied.

RESULTS

Eighty-three benign and thirty-two malignant lesions were histopathologically diagnosed. The minimum, mean, and maximum elasticity values, and the mass/fat elasticity ratios of malignant lesions, were significantly higher than those of benign lesions. The cutoff value was 45.7 kPa for mean elasticity (sensitivity, 96%; specificity, 95%), 54.3 kPa for maximum elasticity (sensitivity, 95%; specificity, 94%), 37.1 kPa for minimum elasticity (sensitivity, 96%; specificity, 95%), and 4.6 for the mass/fat elasticity ratio (sensitivity, 97%; specificity, 95%).

CONCLUSION

SWE yields additional valuable quantitative data to ultrasonographic examination on solid breast lesions. SWE may serve as a complementary tool for diagnosis of breast lesions. Long-term clinical studies are required to accurately select lesions requiring biopsy.