E-ISSN: 1305-3612
Value of pre-intervention CT perfusion imaging in acute ischemic stroke prognosis
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Interventional Radiology - Review
VOLUME: 27 ISSUE: 6
P: 774-785
November 2021

Value of pre-intervention CT perfusion imaging in acute ischemic stroke prognosis

Diagn Interv Radiol 2021;27(6):774-785
DOI: 10.5152/dir.2021.20805
Anubhav Katyal 1,2
Sonu Menachem Maimonides Bhaskar 1,3,2,4,5,6
1. Neurovascular Imaging Laboratory, Ingham Institute for Applied Medical Research, Clinical Sciences Stream, Sydney, Australia
2. University of New South Wales (UNSW), South Western Sydney Clinical School, NSW, Australia
3. Department of Neurology & Neurophysiology, Liverpool Hospital & South West Sydney Local Health District (SWSLHD), Sydney, Australia
4. Ingham Institute for Applied Medical Research, Stroke & Neurology Research Group, Sydney, Australia
5. NSW Brain Clot Bank, NSW Health Statewide Biobank and NSW Health Pathology, Sydney, NSW, Australia
6. Thrombolysis and Endovascular WorkFLOw Network (TEFLON), Sydney, Australia
No information available.
No information available
Received Date: 04.10.2020
Accepted Date: 31.10.2020
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ABSTRACT

Noninvasive imaging plays an important role in acute stroke towards diagnosis and ongoing management of patients. Systemic thrombolysis and endovascular thrombectomy (EVT) are proven treatments currently used in standards of care in acute stroke settings. The role of computed tomography angiography (CTA) in selecting patients with large vessel occlusion for EVT is well established. However, the value of CT perfusion (CTP) imaging in predicting outcomes after stroke remains ambiguous. This article critically evaluates the value of multimodal CT imaging in early diagnosis and prognosis of acute ischemic stroke with a focus on the role of CTP in delineating tissue characteristics, patient selection, and outcomes after reperfusion therapy. Insights on various technical and clinical considerations relevant to CTP applications in acute ischemic stroke, recommendations for existing workflow, and future areas of research are discussed.