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Abstract
Aspergillosis may complicate the course of a patient in an immunocompromised state. However, Aspergillus infection is rarely encountered in an immunocompetent host. We present an extremely rare case of Aspergillus chest wall involvement associated with extensive mediastinal lymphadenopathy in an immunocompetent host. A chest wall lesion was the initial indication of underlying nodal disease. We highlight the importance of obtaining early tissue samples in these cases to enable prompt treatment.