Diagnostic and Interventional Radiology
Abdominal Imaging - Original Article

Correlation of clinical and MRI staging in cervical carcinoma treated with radiation therapy: a single-center experience

1.

Departments of Radiation Oncology, Hacettepe University School of Medicine, Ankara, Turkey

2.

Department of Radiation Oncology, İstanbul University İstanbul Faculty of Medicine, İstanbul, Turkey

3.

Department of Radiology, İstanbul University Cerrahpaşa Faculty of Medicine, İstanbul, Turkey

4.

Department of Public Health, İstanbul University İstanbul Faculty of Medicine, İstanbul, Turkey

5.

Department of Radiation Oncology, İstanbul University İstanbul Faculty of Medicine, İstanbul, Turkey

Diagn Interv Radiol 2011; 17: 44-51
DOI: 10.4261/1305-3825.DIR.3114-09.1
Read: 1201 Downloads: 927 Published: 03 September 2019

Abstract

PURPOSE
To correlate clinical and MRI findings in patients with cervical carcinoma treated with radiation therapy (RT).

 

MATERIALS AND METHODS
Forty-two patients with pretreatment IB–IVA cervical carcinoma were included in this retrospective study. Pre- and post-treatment MRI findings of the patients were reevaluated and compared with clinical staging. Six-month, one-year, and two-year follow-up imaging by MR was performed for 36, 20, and 7 patients, respectively. The correlation between clinical and MRI findings was assessed by a Spearman's rho (rank correlation) test. Univariate analyses were performed to identify the prognostic significance of the tumor volume and lymph node status.

 

RESULTS
Pre-treatment correlations between MRI and clinical findings for diagnoses without parametrial invasion, with parametrial invasion, and with pelvic sidewall invasion were 71.0%, 64.7%, and 15.8%, respectively. According to the Spearman's rho (rank correlation) test, the parametrial invasion correlation was poor (r = 0.410, P < 0.01). The correlation of clinical and MRI findings at 6 months was 88.9% (r = 0.674, P < 0.0001).

 

CONCLUSION
In advanced cervical cancer, the correlation of clinical and MRI staging prior to neoadjuvant RT was low despite a high correspondence in the assessment of local response after RT.

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