Diagnostic and Interventional Radiology
Neuroradiology - Pictorial Essay

CT and MRI in the evaluation of craniospinal involvement with polyostotic fibrous dysplasia in McCune-Albright syndrome

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Department of Radiology, Near East University School of Medicine, Nicosia, Northern Cyprus

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Department of Radiology, Gülhane Military Medical Academy, Ankara, Turkey

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From the Department of Radiology, Gülhane Military Medical Academy School of Medicine, Ankara, Turkey

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Department of Radiology (M.K. *), Gülhane Military Medical Academy, Ankara, Turkey.

Diagn Interv Radiol 2008; 14: 177-181
Read: 479 Downloads: 463 Published: 03 September 2019

Abstract

 

In this study, the efficacy of computed tomography (CT) and magnetic resonance imaging (MRI) in the evaluation of craniospinal involvement with polyostotic fibrous dysplasia (PFD) in McCune-Albright syndrome (MAS) and related complications were reviewed. In CT, ground-glass appearance with welldefined borders was seen, with medullary widening and cortical thinning. More rarely, cystic/necrotic areas were observed within involved bone. These lesions were seen as hypointense in T1-weighted sequences and as hyperintense in T2-weighted sequences of MRI. There was no heterogeneous contrast enhancement. Cystic/necrotic areas were seen as hyperintense images on T2-weighted sequences. While bone marrow involvement was shown more clearly with MRI, compression of cranial and spinal nerves was determined most effectively by evaluation of CT and MRI together. CT and MRI should be employed together in order to demonstrate the extent of disease, and complications of craniospinal involvement of PFD in patients with MAS.
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EISSN 1305-3612