Diagnostic and Interventional Radiology
Breast Radiology - Original Article

Effectiveness of single-session ultrasound-guided percutaneous ethanol sclerotherapy in simple breast cysts


Department of Radiology, Yeditepe University Hospital, İstanbul, Turkey

Diagn Interv Radiol 2016; 22: 220-223
DOI: 10.5152/dir.2015.15425
Read: 1171 Downloads: 357 Published: 03 September 2019


We aimed to evaluate the effectiveness of single-session ultrasound-guided percutaneous ethanol sclerotherapy in simple breast cysts.


From January 2002 to January 2014, 35 simple breast cysts (mean volume, 8.2 mL; range, 4–33 mL) in 28 females (mean age, 39 years) were evaluated. In a single session, all cysts were aspirated using 20G needles, refilled with 99% ethanol (90% of the volume of the aspirated fluid), and reaspirated completely after 10 minutes of exposure under ultrasound guidance. Follow-up ultrasonography examinations were performed at one week, one month, three months, and six months for all patients and 12 months, 18 months, and 24 months for available patients. Follow- up duration varied between 6 and 24 months (mean, 15 months).


The technical success rate of ultrasound-guided percutaneous etha­nol sclerotherapy was 97%. The needle tip was dislocated and ethanol was given into the breast parenchyma in one patient (3%). One cyst (3%) was reaspirated at the first week follow-up due to intracystic hemorrhage. Of the 34 cysts treated, 25 (74%) completely responded to therapy and were no longer detectable  on follow-up examinations. Eight cysts (24%) significantly decreased in size and then completely disappeared at six months. At the end of the follow-up period, the clinical success rate reached 100%, and none of the cysts were visible. Except mild to moderate sensation of burning or pain which disappeared or subsided significantly in a couple of minutes, no other complications were observed in patients.


Ultrasound-guided ethanol sclerotherapy is a fast, safe, and highly effective method in the treatment of simple breast cysts.

EISSN 1305-3612