Diagnostic and Interventional Radiology
Abdominal Imaging - Pictorial Essay

Focal lesions in cirrhotic liver: what else beyond hepatocellular carcinoma?


Section of Radiology -Di.Bi.Me.F., University of Palermo, Palermo, Italy


Department of Radiology, Duke University Medical Center, Durham, North Carolina, USA


Department of Radiology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA


Section of Gastroenterology -Di.Bi.Mi.S., University of Palermo, Palermo, Italy;


IPMA Laboratory, U773 INSERM University Paris Diderot, Sorbonne Paris Cité Department of Radiology, Beaujon University Hospital Paris, Clichy, France.

Diagn Interv Radiol 2014; 20: 222-228
DOI: 10.5152/dir.2014.13184
Read: 1159 Downloads: 696 Published: 03 September 2019


Detection and characterization of focal lesions in the cirrhotic liver may pose a diagnostic dilemma. Several benign and malignant lesions may be found in a cirrhotic liver along with hepatocellular carcinoma (HCC), and may exhibit typical or atypical imaging features. In this pictorial essay, we illustrate computed tomography and magnetic resonance imaging findings of lesions such as simple bile duct cysts, hemangioma, focal nodular hyperplasia-like nodules, peribiliary cysts, intrahepatic cholangiocarcinoma, lymphoma, and metastases, all of which occur in cirrhotic livers with varying prevalences. Pseudolesions, such as perfusion anomalies, focal confluent fibrosis, and segmental hyperplasia, will also be discussed. Imaging characterization of non-HCC lesions in cirrhosis is important in formulating an accurate diagnosis and triaging the patient towards the most appropriate management.

EISSN 1305-3612