Diagnostic and Interventional Radiology
Abdominal Imaging - Original Article
Is visceral obesity associated with colorectal cancer? The first volumetric study using all CT slices

Is visceral obesity associated with colorectal cancer? The first volumetric study using all CT slices

1.

Department of Radiology, University of Health Sciences, Gülhane Training and Research Hospital, Ankara, Turkey

2.

Department of General Surgery, University of Health Sciences, Gülhane Training and Research Hospital, Ankara, Turkey

Diagn Interv Radiol 2019; 25: 338-345
DOI: 10.5152/dir.2019.18350
Read: 46 Downloads: 26 Published: 07 October 2019

PURPOSE

We aimed to examine the possible relationship between abdominal adiposity parameters and the presence of colorectal cancer (CRC) and between these adiposity parameters and various histopathologic findings of the tumor.

METHODS

A total of 60 control subjects and 111 CRC patients, 63 with early-stage and 48 with advanced-stage disease, were enrolled. Medical data and abdominopelvic computed tomography (CT) examinations of each study group were retrospectively reviewed. Abdominal adiposity parameters, including visceral adipose tissue (VAT) volume, subcutaneous adipose tissue (SAT) volume, and total adipose tissue (TAT) volume, were calculated on all slices of the CT examinations with specialized software, and results for each study group were compared. Adiposity parameters were also compared with tumor histopathologic findings.

RESULTS

We found lower VAT and higher SAT volumes in advanced-stage CRC patients, compared with the early-stage group. However, this relationship was not statistically significant (P = 0.721 for VAT and P = 0.432 for SAT volumes). We detected significantly lower VAT and SAT volumes in the early-stage CRC group compared with the control group (P = 0.014 for both). There was no significant relationship between TAT volumes and the study groups (P = 0.06). No statistically significant relationship was detected between adipose tissue parameters and histopathologic features of the CRC group (P > 0.05).

CONCLUSION

We found statistically significant lower VAT and SAT volumes in patients with early-stage CRC compared with the control group. Volumetric adipose tissue measurements may be more accurate than area measurements and can easily be performed on abdominopelvic CT examination, which is the routine imaging modality for CRC patients.

 

You may cite this article as: Akay S, Urkan M, Balyemez U, Erşen M, Taşar M. Is visceral obesity associated with colorectal cancer? The first volumetric study using all CT slices. Diagn Interv Radiol 2019; 25:338–345.

Files
EISSN 1305-3612
3