Diagnostic and Interventional Radiology
Neuroradiology - Case Report 2016

Osmotic demyelination syndrome in a 40-day-old infant

1.

Department of Radiology, İnönü University School of Medicine, Turgut Özal Medical Center, Malatya,Turkey;

2.

Departments of Radiology, İnönü University School of Medicine, Malatya, Turkey.

3.

From the Departments of Pediatrics, İnönü University School of Medicine, Malatya, Turkey.

Diagn Interv Radiol 2007; 13: 121-124
Read: 475 Downloads: 417 Published: 03 September 2019

Abstract

Osmotic demyelination syndrome refers to the myelin destruction of various brain structures that follows osmotic stress. It affects myelinated brain; therefore, it is very rare in babies and it has not been reported in patients younger than 10 months of age. Herein, we present a 40-day-old infant with osmotic demyelination syndrome, along with imaging findings. Her pontine and thalamic lesions regressed during the 10-day treatment course, whereas demyelinated areas in the lentiform nucleus persisted. Magnetic resonance spectroscopy of the latter revealed decreased levels of all major metabolites. Imaging findings remained unchanged after that phase.

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