Diagnostic and Interventional Radiology
Chest Imaging - Original Article

Role of MR spectroscopy in differential diagnosis of solitary pulmonary lesions


Department of Radiology, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey

Diagn Interv Radiol 2020; 1: -
Read: 459 Published: 19 October 2020

PURPOSE: The aim of our study was to evaluate the availability of Magnetic Resonance Spectroscopy (MRS) for the differentiation of benign or malignant pulmonary nodules and masses.

METHODS: A total of 59 patients (45 male, 14 female) with pulmonary nodules and masses were included in this prospective study. MRS was applied to the pulmonary lesions of the patients and choline levels were determined. Afterwards CT-guided percutaneous needle biopsy was performed. According to the biopsy results, pulmonary lesions in 25 patients were benign and pulmonary lesions in 34 patients were malignant.

RESULTS: Choline levels were significantly higher in malignant group compared to benign group (P < 0.001). When the other conditions were kept constant, the probability of malignancy was increased significantly 17.38 times (95% CI: 3.78-79.93) in those with choline levels above 1.65 compared to those with choline levels below 1.65 (P < 0.001).

CONCLUSION: MRS, which is a non-invasive method, can be used in the differential diagnosis of pulmonary nodules and masses.

EISSN 1305-3612