Diagnostic and Interventional Radiology
General Radiology - Review

The role of dynamic contrast-enhanced MRI in cancer diagnosis and treatment


Molecular Imaging Program, National Cancer Institute National Institutes of Health, Bethesda, Maryland, USA


Clinical Center Radiology and Imaging Sciences, National Institutes of Health, Bethesda, Maryland, USA


Philips Healthcare Cleveland, Ohio, USA

Diagn Interv Radiol 2010; 16: 186-192
DOI: 10.4261/1305-3825.DIR.2537-08.1
Read: 1065 Downloads: 954 Published: 03 September 2019


Angiogenesis is a key step in the pathophysiology of tumor growth and metastatic spread. Recently, dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) has emerged as a method for assessing angiogenesis both during the initial diagnosis and for follow up of anti-angiogenic therapies. In this review, we discuss the technical aspects of implementing DCE-MRI in clinical practice with emphasis on acquisition methods and analytic techniques.

EISSN 1305-3612