Diagnostic and Interventional Radiology
Interventional Radiology - Original Article

US-guided percutaneous thrombin injection of postcatheterization pseudoaneurysms


Department of Radiology, Abant İzzet Baysal University School of Medicine, Bolu, Turkey.


Department of Radiology, Şifa Hospital, İzmir, Turkey.


Department of Radiology , Başkent University School of Medicine Research and Training Hospital, Adana, Turkey.


Department of Radiology, Dicle University School of Medicine, Diyarbakır, Turkey


Department of Radiology, Dicle University School of Medicine, Diyarbakır, Turkey


Department of Radiology, Bahçelievler Medical Park Hospital, İstanbul, Turkey

Diagn Interv Radiol 2012; 18: 319-325
DOI: 10.4261/1305-3825.DIR.4933-11.1
Read: 664 Downloads: 554 Published: 03 September 2019


This study retrospectively evaluated ultrasonography-guided (US-guided) percutaneous thrombin injection for the treatment of postcatheterization femoral and brachial artery pseudoaneurysms.


Fifty-five patients with postcatheterization femoral artery (n=53) or brachial artery (n=2) pseudoaneurysms were treated using US-guided human thrombin (500 IU/mL) injection. Pseudoaneurysm size, thrombin dose, therapy outcome, and complications were documented. Follow-up color Doppler US was performed 7 and 30 days after treatment. Short-duration supplemental compression was applied to six patients at the first week follow-up examination after a reinjection of thrombin had failed.


Mean pseudoaneurysm volume was 20.3±18.7 cm3. The mean injected thrombin dose was 478±238 IU. Thirty-eight (69.1%) of the 55 pseudoaneurysms were thrombosed with a single injection, and 11 of 17 pseudoaneurysms were thrombosed after a second injection. All (100%) of the 41 pseudoaneurysms that were diagnosed within the first two weeks of postcatheterization were successfully treated. The overall primary success rate was 89.1% (49 of 55 pseudoaneurysms). Supplemental compression promoted thrombosis in four of the six patients who had treatment failure with thrombin injection. The secondary success rate was 96.4% (53 of 55 pseudoaneurysms). There were no complications.


US-guided thrombin injection was most successful within the first two weeks, and the supplemental compression might aid in the closure of partially thrombosed pseudoaneurysms.

EISSN 1305-3612