E-ISSN 1305-3612
1 Department of Radiology, Dokuz Eylül University School of Medicine, İzmir, Turkey  
2 Department of Radiology, Ege University School of Medicine, İzmir, Turkey  
3 Department of Radiology, Ondokuz Mayıs University School of Medicine, Samsun, Turkey  
4 Department of Pathology, Dokuz Eylul University School of Medicine, İzmir, Turkey  
Diagn Interv Radiol ; : -


Purpose: To evaluate magnetic resonance imaging (MRI) features, including signal intensities, enhancement patterns and T2 signal intensity ratios to differentiate oncocytoma from chromophobe renal cell carcinoma (RCC).


Methods: This retrospective study included 17 patients with oncocytoma and 33 patients with chromophobe RCC who underwent dynamic MRI. Two radiologists independently reviewed images blinded to pathology. Morphologic characteristics, T1-T2 signal intensities were reviewed. T2 signal intensities, wash-in, wash-out values, T2 signal intensity ratios were calculated. Sensitivity and specificity analyses were performed.


Results: Mean ages of patients with oncocytoma and chromophobe RCC were 61.0 ± 11.6 and 58.5 ± 14.0 years, respectively. Mean tumor size was 60.6 ± 47.3 mm for oncocytoma, 61.7 ± 45.9 mm for chromophobe RCC. Qualitative imaging findings in conventional MRI have no distinctive feature in discrimination of two tumors. Regarding signal intensity ratios, oncocytomas were higher than chromophobe RCCs. Renal oncocytomas showed higher signal intensity ratios and wash-in values than chromophobe RCCs in all phases. Fast-spin echo T2 signal intensities were higher in oncocytomas than chromophobe RCCs.


Conclusion: Signal intensity ratios, fast-spin echo T2 signal intensities and wash-in values constitute diagnostic criteria for discriminating between oncoytomas and chromophobes. In the excretory phase of dynamic enhanced images, oncocytomas have higher signal intensity ratio than chromophobe RCC and high wash-in values strongly imply a diagnosis of renal oncocytoma.

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