E-ISSN 1305-3612
Interventional Radiology - Review
Laser angioplasty of peripheral arteries: basic principles, current clinical studies, and future directions
1 Department of Cardiology, Charles University, 3rd School of Medicine, Prague, Czech Republic  
Diagn Interv Radiol 2019; 25: 392-397
DOI: 10.5152/dir.2019.18515
Abstract

 

Percutaneous transluminal angioplasty (PTA) is a routine procedure for the treatment of peripheral arterial disease. However, its main limitation is late restenosis occurring at a 1-year rate of 6%–60%. Restenosis arises from injury to the arterial wall including overstretching, compression and rupture of the atherosclerotic plaque during balloon inflation. It is hypothesized that better long-term angioplasty results are observed if atherosclerotic plaques are removed rather than compressed and fractured. Laser angioplasty is one method to remove atherosclerotic plaques. We discuss the principles of lasers, physical properties of laser light, history of laser angioplasty and effects of laser radiation on tissues. Large clinical studies using laser angioplasty are critically assessed. In comparison to conventional PTA, there are some advantages of laser angioplasty: easier passage through chronic and calcified occlusions and according to some studies, better short- and medium-term results regarding limb salvage and management of in-stent restenoses.

 

 

You may cite this article as: Stanek F. Laser angioplasty of peripheral arteries: basic principles, current clinical studies, and future directions. Diagn Interv Radiol 2019; 25:392–397.

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