ISSN 1305-3825 | E-ISSN 1305-3612
Pediatric Radiology - Original Article 2016
Evaluation of hippocampal infolding angle and incomplete hippocampal inversion in pediatric patients with epilepsy and febrile seizures
1 Department of Radiology, Afyon Kocatepe University School of Medicine, Afyonkarahisar, Turkey  
2 Department of Pediatrics, Afyon Kocatepe University School of Medicine, Afyonkarahisar, Turkey  
Diagn Interv Radiol ; : -

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Purpose: The purpose of this study was to investigate the frequency of incomplete hippocampal inversion (IHI) and the hippocampal infolding angle (HIA) in pediatric patients without additional abnormal findings in the brain.


Methods: Eighty-three patients with epilepsy, 49 patients with febrile convulsion and 74 patients in the control group were included between September 2012 and February 2015. Presence of IHI was evaluated and HIA was measured on MRI.


Results: IHI was found in 23 patients (27.7%) in the epilepsy group, 15 (30.6%) in the febrile convulsion group, and 14 (19.0%) in the control group without a significant difference between any of the groups (P:0.27). Comparing with the epilepsy and febrile convulsion groups, the HIA was significantly larger in the control group in the sections of the right cerebral pedincule, the left cerebral pedincule and the right superior cerebellar pedincule. No correlation was found between the laterality of the epileptogenic focus in the epilepsy group and existence of IHI, nor between age and HIA values among all groups.


Conclusion: Although IHI is not an uncommon abnormality in the normal pediatric population, decreased HIA is more frequently found in patients with epilepsy or febrile convulsions.

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