E-ISSN 1305-3612
Gu Tao 1 ,  
Guo Tan 1 ,  
1 Department of Radiology, Beijing Hospital, National Center of Gerontology, Beijing, China  
Diagn Interv Radiol ; : -


Purpose: To evaluate the success rate and complication occurrence of CT-guided localization with medical adhesive injection for treatment of small pure ground-glass nodules (pGGNs) and mixed ground-glass nodules (mGGNs) with video-assisted thoracoscopic surgery (VATS).


Methods: From March 2015 to May 2017, 41 patients with 44 small pGGNs and mGGNs underwent CT-guided percutaneous localization with medical adhesive prior to wedge resection by VATS.


Results: Localization with medical adhesive was successful in all patients (100%). The 44 nodules (13 pGGNs, 31 mGGNs) had a mean maximal long-axis diameter (9±4mm) and a mean distance (10±7mm) from the most superficial edge of nodule to the visceral pleura. The localization time was (16±8) minutes. A medium inverse relationship between localization time and diameter of nodules was observed (r=-0.42, p=0.005). Thirty-three nodules with primary lung cancer were pathologically confirmed. There were 3 cases of pneumothorax (7%), 3 cases of parenchyma hemorrhage (7%) and 2 cases of irritable cough (5%), respectively. No conversion to thoracotomy was necessary in any patient.


Conclusion: CT-guided percutaneous localization with medical adhesive can label small pGGNs and mGGNs prior to VATS, with a high success rate and low complication frequency.

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