E-ISSN 1305-3612
1 Department of Radiology, Mayo Clinic, Rochester, Minnesota, USA  
2 Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA  
Diagn Interv Radiol ; : -



Purpose: To evaluate the imaging features of bile duct adenoma (BDA) on ultrasound (US), computed tomography (CT) and magnetic resonance imaging (MRI).


Methods: Retrospective search in our institution data base was performed for histologically confirmed BDA. Their imaging studies before histological confirmation were reviewed. The search identified 7 adults (mean age, 52.9 years) with histologically proven single BDA each. US (n=3); CT (n=5); and MRI (n=3) were performed before histological confirmation. Additionally, a systematic English literature review for BDA and reported imaging findings since 2000 was also conducted using the following search criteria “bile duct adenoma, peribiliary hamartoma, biliary adenoma, CT, ultrasound, MRI” (date range: 01/01/2000 through 08/31/2016). The imaging findings of those cases reported were summarized and compared with our series.


Results: All the seven individual nodules were well circumscribed. Five lesions were located in the right hepatic lobe and two in the left hepatic lobe. On US, lesions appeared hypoechoic (n=2) and hyperechoic (n=1).  BDA was hypodense on non-contrast CT images (n=1). On MRI, BDA were hypointense on T1 (n=3), hyperintense on T2 (n=3) and hyperintense on diffusion weighted images (n=2). On post contrast enhanced CT and MRI, BDAs showed arterial phase hyperenhancement that persisted on portal venous/delayed phase images.


Conclusion: BDA demonstrates characteristic arterial phase hyperenhancement that persisted into the portal venous and delayed phases on CT and MRI which may be useful in differentiating from other hepatic lesions.

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