E-ISSN 1305-3612
Interventional Radiology - Original Article
Ultrasound guided core needle biopsy in diagnosing small lymph node metastases adjacent to cervical large vessels under assistance of hydrodissection
1 Department of Interventional Ultrasound, Chinese PLA General Hospital, Beijing, People’s Republic of China  
Diagn Interv Radiol ; : -



Purpose: To evaluate the safety and efficacy of ultrasound (US) guided core needle biopsy (CNB) with hydrodissection to diagnose small lymph node metastases adjacent to cervical large vessels.

Methods: From January 2013 to October 2017, 31 patients with 31 cervical lymph node metastases adjacent to large vessels presented from US-guided CNB. The mean maximal diameter of lymph nodes was 0.93±0.16 cm (ranging from 0.6 to 1.2 cm). All patients underwent US-guided CNB with 18 gauge true-cut biopsy needle after hydrodissection with saline. The separation success rate (SSR) of the hydrodissection, technique success rate (TSR) of CNB, histopathology success rate (HST), and complications were assessed.

Results: The SSR of hydrodissection was 100% (31/31). After the effective separation between the lymph node metastases and the adjacent large vessels with saline injection, the procedures of CNB were performed with TSR of 100% (31/31).  The HST of the lymph node metastases was 100% (31/31). Two patients complained of mild cervical swelling sensation during saline injection. No major complications including injury of the large vessels and massive haemorrhage occurred.

Conclusion: Hydrodissection can facilitate safe and effective US-guided CNB of subcentimeter cervical lymph nodes adjacent to large vessels, potentially impacting further therapeutic decisions.

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